Spirulina and Muscle Damage

Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress.

1: Eur J Appl Physiol. 2006 Sep;98(2):220-6. Epub 2006 Aug 30.

  • Lu HK,
  • Hsieh CC,
  • Hsu JJ,
  • Yang YK,
  • Chou HN.


Sport Science Research Center, National Taiwan College of Physical Education, Taichung, Taiwan. hklu@ntcpe.edu.tw

The effects of spirulina supplementation on preventing skeletal muscle damage on untrained human beings were examined. Sixteen students volunteered to take Spirulina platensis in addition to their normal diet for 3-weeks. Blood samples were taken after finishing the Bruce incremental treadmill exercise before and after treatment. The results showed that plasma concentrations of malondialdehyde (MDA) were significantly decreased after supplementation with spirulina (P < 0.05).="" the="" activity="" of="" blood="" superoxide="" dismutase="" (sod)="" was="" significantly="" raised="" after="" supplementation="" with="" spirulina="" or="" soy="" protein="" (p="">< 0.05).="" both="" of="" the="" blood="" glutathione="" peroxidaes="" (gpx)="" and="" lactate="" dehydrogenase="" (ldh)="" levels="" were="" significantly="" different="" between="" spirulina="" and="" soy="" protein="" supplementation="" by="" an="" ancova="" analysis="" (p="">< 0.05).="" in="" addition,="" the="" lactate="" (la)="" concentration="" was="" higher="" and="" the="" time="" to="" exhaustion="" (te)="" was="" significantly="" extended="" in="" the="" spirulina="" trail="" (p="">< 0.05).="" these="" results="" suggest="" that="" ingestion="" of="" s.="" platensis="" showed="" preventive="" effect="" of="" the="" skeletal="" muscle="" damage="" and="" that="" probably="" led="" to="" postponement="" of="" the="" time="" of="" exhaustion="" during="" the="" all-out="" exercise.="">
PMID: 16944194 [PubMed - indexed for MEDLINE]


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